34 Results for "

Ainsliaea fragrans Champ.

" in MedChemExpress (MCE) Product Catalog:
Products (34)

34 Results for "Ainsliaea fragrans Champ." in MCE Product Catalog:

6
6 Cited Publications
Cat. No.: HY-N0064
CAS No.: 107534-93-0
Synonyms: (+)-Anwulignan; Anwuligan
Macelignan ((+)-Anwulignan; Anwuligan)?is an orally active lignan isolated from Myristica fragrans. Macelignan possesses many pharmacological activities, including anti-inflammatory, anti-cancer, anti-diabetes, and neuroprotective activities .
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1
1 Cited Publications
Cat. No.: HY-N0479
CAS No.: 51020-87-2
Synonyms: (-)-Licarin B
Licarin B, a nitric oxide production inhibitor extracted from the component of the seeds of Myristica fragrans, improves insulin sensitivity via PPARγ and activation of GLUT4 in the IRS-1/PI3K/AKT pathway .
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Cat. No.: HY-W004294
CAS No.: 112-72-1
1-Tetradecanol is a straight-chain saturated fatty alcohol and antibacterial agent. 1-Tetradecanol can be isolated from Myristica fragrans. 1-Tetradecanol possesses antibacterial and anti-inflammatory (periodontitis) activity .
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Cat. No.: HY-N2511
CAS No.: 555-45-3
Trimyristin is an orally active compound. Trimyristin can be isolated from the seeds of nutmeg (Myristica fragrans). Trimyristin inhibits the activities of acetylcholinesterase (AChE), ACP and ALP, with IC50 values of 0.11, 0.16 and 0.18 mM, respectively. Trimyristin exerts competitive-noncompetitive inhibition on acetylcholinesterase, uncompetitive inhibition on ACP, and competitive/noncompetitive inhibition on ALP. Trimyristin restores the downregulated acetylcholinesterase concentration in the cerebral cortex of rats exposed to sodium arsenite. Trimyristin can be used in studies related to fascioliasis and neurotoxicity .
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Cat. No.: HY-N4031
CAS No.: 82375-29-9
Humantenine is a highly toxic indole alkaloid from Gelsemium elegans (Gardn. & Champ.) Benth. that binds to RNA m6A modification regulatory proteins (ALKBH5, METTL). Humantenine stably binds via hydrogen bonding and hydrophobic interactions and disrupts the m6A methylation level of target genes, thereby impairing the expression of intestinal epithelial cell tight junction and cytoskeleton-related genes, causing intestinal barrier dysfunction and significant intestinal cytotoxicity. The intraperitoneal injection LD50 values of Humantenine are <1 mg/kg in mice, 1.2 mg/kg in male rats and 1.5 mg/kg in female rats, respectively. Species differences exist in the metabolism of Humantenine in human, porcine, goat and rat liver microsomes, and demethylation, dehydrogenation and oxidation occur in liver microsomes .
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Cat. No.: HY-N11108
CAS No.: 87606-12-0
Gochnatiolide A is a dimeric sesquiterpene that can be found in Ainsliaea henryi. Gochnatiolide A exhibits antiproliferative activity against the kidney, melanoma, ovarian-resistant and glioma cell lines .
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Cat. No.: HY-N10396
CAS No.: 83198-63-4
Synonyms: (+)-Verrucosin
Verrucosin (Compound 3) is a compound isolated from Myristica fragrans .
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Cat. No.: HY-N6873
CAS No.: 60037-39-0
GL3, the major component of O. fragrans seeds, is a derivative based on both phenylethanoid and methyloleoside .
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Cat. No.: HY-N2207
CAS No.: 178740-32-4
rel-(8R,8'R)-Dimethyl-(7S,7'R)-bis(3,4-methylenedioxyphenyl)tetrahydro-furan is a chemical constituent of the fruit of Myristica fragrans.
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Cat. No.: HY-W004294S1
CAS No.: 169398-02-1
1-Tetradecanol-d2 is the deuterium labeled 1-Tetradecanol . 1-Tetradecanol, isolated from Myristica fragrans, is a straight-chain saturated fatty alcohol. 1-Tetradecanol possesses antibacterial and anti-inflammatory (periodontitis) activity .
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Cat. No.: HY-N7394
CAS No.: 528-64-3
Synonyms: (3S)-Zuonin A
Galbacin ((3S)-Zuonin A), the epimer of (-)-Zuonin A (HY-N7394A), is a AMPK activator. Galbacin can be isolated from Myristica fragrans (nutmeg). Galbacin stimulates AMPK enzyme in differentiated C2C12 cells. Galbacin also has anticancer activity, and inhibits the proliferation of lymphocyte and tumor cells. Galbacin prevents weight gain in diet-induced mice model. Galbacin can be used for metabolic syndrome (including obesity and type-2 diabetes) and caners research .
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Cat. No.: HY-153881
CAS No.: 2768099-51-8
Target:  

Ras

Domaines de recherche:  

Cancer

KRAS G12C degrader-1 (Compound 283) is a potent KRAS G12C degrader (DC50: < 100 nM) for cancer research. KRAS G12C degrader-1 is a chaperone (HSP90)-mediated protein degrader (CHAMPs) .
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Cat. No.: HY-N0608A
CAS No.: 41535-95-9
(Rac)-Myrislignan is the racemate of Myrislignan. Myrislignan, a lignan isolated from Myristica fragrans Houtt, possesses anti-inflammatory activities. Myrislignan attenuates LPS-induced inflammation reaction in murine macrophage cells through inhibition of NF-kB signalling pathway activation .
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Cat. No.: HY-RS02596
Domaines de recherche:  

Others

CHAMP1 Human Pre-designed siRNA Set A contains three designed siRNAs for CHAMP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-N12478
CAS No.: 1039431-94-1
Ainsliadimer A is a sesquiterpene lactone dimer with an unusual carbon skeleton. Ainsliadimer A can be obtained from from Ainsliaea macrocephala. Ainsliadimer A inhibits the production of nitric oxide in cells stimulated by LPS .
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Cat. No.: HY-N12349
CAS No.: 57576-33-7
Glucozaluzanin C is a lignan isolated from the MeOH extract of the roots of Ainsliaea acerifolia (Compositae). Glucozaluzanin C has ED50 value of 2.45 μg/mL, 1.37μg/mL, 0.40 μg/mL, 1.41 μg/mL, 1.43 μg/mL for A549 cells, SK-OV-3 cells, SK-MEL-2 cells, XF498 cells, HCT15 cells, respectively .
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Cat. No.: HY-N10397
CAS No.: 1314042-85-7
Maceneolignan H (Compound 8) is a neolignane compound isolated from the arils of Myristica fragrans. Maceneolignan H is a selective CCR3 antagonist (EC50 = 1.4 μM). Maceneolignan H has the potential for the research of allergic diseases .
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Cat. No.: HY-N5138
CAS No.: 891182-93-7
Odoratisol A is found in Myristica fragrans .
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Cat. No.: HY-N17623
CAS No.: 1714097-11-6
Ainsliaeasin C, a 7-hydroxycoumarin derivative, is an orally active anticoagulant agent that can be found in Ainsliaea fragrans. Ainsliaeasin C exerts anticoagulant activity both in vitro and in vivo. Ainsliaeasin C can be used for the research on thrombotic disorders .
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Cat. No.: HY-W004294S
CAS No.: 284474-78-8
1-Tetradecanol-d29 is the deuterium labeled 1-Tetradecanol . 1-Tetradecanol, isolated from Myristica fragrans, is a straight-chain saturated fatty alcohol. 1-Tetradecanol possesses antibacterial and anti-inflammatory (periodontitis) activity .
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